TRANSLATIONAL NEURO-ONCOLOGY LABORATORIES (TNOL)

SANTOSH  KESARI,  MD, PhD

1.         Kesari S*, Bundock EA. Punched-out skull. Archives of Neurology 2004;61(6):958-9.
*Senior/corresponding author

2.         Kesari S*. Digital rendition of visual migraines. Archives of Neurology 2004;61(9):1464-5.
*Senior/corresponding author

3.         Narin O, Drappatz J, Doherty LM, Wen PY, Kesari S*.  Cerebrospinal fluid spread of anaplastic glioma. Journal of Clinical Oncology 2007;25(5):596-7.
*Senior/corresponding author

4.         Gerin F, Baloglu O, Morgan JA, Kesari S*. Central nervous system metastases from imatinib mesylate resistant gastrointestinal stromal tumor.  Journal of Neuro-Oncology 2007;82(2):227-8.
*Senior/corresponding author

5.         Santagata S. Kesari S, Black PM, Chan JA.  Anaplastic variant of medulloblastoma mimicking a vestibular schwannoma. Journal of Neuro-Oncology 2007;81(1):49-51.

6.         Monje ML, Ramakrishna NR, Young G, Drappatz J, Doherty LM, Wen PY, Kesari S*.  Durable response of a radiation-induced, high-grade cerebellar glioma to temozolomide. Journal of Neuro-Oncology 2007; 84(2):179-83.
*Senior/corresponding author

7.         Chheda MG, Drappatz J, Greenberger NJ, Kesari S, Weiss SE, Gigas DC, Doherty LM, Wen PY. Hepatitis B reactivation during glioblastoma treatment with temozolomide: A cautionary note. Neurology 2007;68(12):955-6.

8.         Wabulya A, Imitola J, Santagata S, Kesari S*. Mycosis fungoides with leptomeningeal involvement. Journal of Clinical Oncology 2007;25(35):5658-61.
*Senior/corresponding author

9.         Akar S, Drappatz J, Hsu L, Blinder RA, Black PM, Kesari S*. Hypertrophic olivary degeneration after resection of a cerebellar tumor. Journal of Neuro-Oncology 2008;87(3):341-5.
*Senior/corresponding author

10.     Saad A, Tuli S, Ali EN, Houtchens M, Delalle I, Kesari S*. Pilocytic astrocytoma of the spinal cord in an adult. Journal of Neuro-Oncology 2008;88(2):189-91.
*Senior/corresponding author

11.     Drappatz J, Akar S, Fisher DC, Samuels MA, Kesari S*. Imaging of Bing-Neel syndrome. Neurology 2008;70(16):1364.
*Senior/corresponding author

12.     Kesari S*, Drappatz J, Akar S, Vergilio J, Wen PY, Soiffer RJ, Stone RM, DeAngelo DJ. Recurrent acute promyelocytic leukemia presenting as a sacral nerve root mass. Journal of Clinical Oncology 2008;26(19):3279-81.
*Senior/corresponding author

13.     Rasper M. Kesari S*. Burkitt lymphoma presenting as a rapidly evolving cavernous sinus syndrome. Archives of Neurology 2008;65(12):1668.*
*Senior/corresponding author

14.     Saad AG, Alyea EP 3rd, Wen PY, DeGirolami U, Kesari S*. Graft-versus-host disease of the CNS after allogeneic bone marrow transplantation. Journal of Clinical Oncology 2009;27(30):e147-9.
*Senior/corresponding author

15.     Xia Z, Mehta BP, Ropper AH, Kesari S*. Paraneoplastic limbic encephalitis presenting as a neurological emergency: a case report; Journal of Medical Case Reports 2010;4:95
*Senior/corresponding author

16.     Housman E, Chang P, Lane SW, Blinder R, Galinsky I, Kesari S, Ho VT, Stone RM, Mullally A. CNS Relapse in Acute Promyeloctyic Leukemia. Journal of Clinical Oncology 2010;28(24):e409-11.

17.     Zhang M, Li F, Rasper M, Saad AG, Kesari S. Prolonged stability of progressive multifocal leukoencephalopathy in a patient with chronic lymphocytic leukemia. Journal of Clinical Oncology 2010;28(28):e503-6.

18.     Pothiawala S, Hsu MY, Yang C, Kesari S, Ibrahimi OA. Urticarial hypersensitivity reaction caused by temozolomide. J Drugs Dermatology 2010;9(9):1142-4.

19.     Yavagal DR, Geng D, Akar S, Buonanno F, Kesari S*. Superficial siderosis of the central nervous system due to bilateral jugular vein thrombosis. Arch Neurol 2010;67(10):1269-71.
*Senior/corresponding author

20.     Rosow L, Jiang JX, Deuel T, Lechpammer M, Zamani AA, Milner DA, Folkerth R, Marty FM, Kesari S*. Cerebral phaeohyphomycosis caused by Bipolaris spicifera after heart transplantation. Transpl Infect Dis 2011;13(4):419-423.
*Senior/corresponding author

21.     Hu XQ, Imitola J, Kim RY, Mahta A, Kesari S*. Brain metastasis from ovarian cancer: case report and review of the literature. Med Oncol 2012;29(2):1250-2.
*Senior/corresponding author

22.     Zhang M, Mahta A, Kim RY, Akar S, Kesari S*. Durable remission of leptomeningeal metastases from hormone-responsive prostate cancer. Med Oncol 2012;29(2):806-8.
*Senior/corresponding author

23.     Hu A, Xu Z, Kim RY, Nguyen A, Lee JW, Kesari S. Seizure control: A secondary benefit of chemotherapeutic temozolomide in brain cancer patients. Epilepsy Res 2011;95(3):270-2.

24.     Mahta A, Kim RY, Kesari S*. Fourth ventricular choroid plexus papilloma. Med Oncol 2012;29(2):1285-6.
*Senior/corresponding author

25.     Moazzam AA, Drappatz J, Kim RY, Kesari S*. Chronic lymphocytic leukemia with central nervous system involvement: report of two cases with a comprehensive literature review. Journal of Neuro-Oncology 2012;106(1):185-200.
*Senior/corresponding author

26.     Mahta A, Kim RY, Fanta PT, Lawson JD, Kesari S*. Leptomeningeal metastasis from appendiceal adenocarcinoma: case report and literature review. Journal of Gastrointestinal Cancer 2011; (epub)
*Senior/corresponding author

27.     Duic JP, Grewal J, McConie K, Staszewski H, Haas J, Kesari S*. Eltrombopag for radiation-induced thrombocytopenia in a glioblastoma patient. Journal of Neuro-Oncology 2012;106(2):427-9.
*Senior/corresponding author

28.     Zeng X, Mahta A, Kim RY, Saad AG, Kesari S*.   Refractory seizures due to a dural-based cavernoma masquerading as a meningioma. Neurol Sci 2012;33(2):441-3.
*Senior/corresponding author

29.     Mahta A, Qu, Y, Nastic D, Sundstrom M, Kim RY, Saria M, Santagata S, Kesari S*.  Relapsing tumefactive lesion in an adult with medulloblastoma previously treated with chemoradiotherapy and stem cell transplant.  Pathol Oncol Res 2012;18(2):539-43.
*Senior/corresponding author

30.     Mahta A, Kim RY, Kesari S*. Progressive multifocal leukoencephalopathy with wallerian degeneration. Eur Neurol 2011;66(4):242.
*Senior/corresponding author

31.     Mahta A, Borys E, Kesari S*. Cerebellar glioneuronal tumor: a case report and review of the literature. Med Oncol 2012;29(3):2038-9.
*Senior/corresponding author

32.     Qu Y, Davis JE, Chi J, Kesari S*. 71-year-old female with right eye proptosis. Brain Pathology. 2011;21(6):709-10.
*Senior/corresponding author

33.     Mahta A, Kim RY, Saad AG, Kesari S*. 47-year-old man with leg numbness. 2011; (epub)
*Senior/corresponding author

34.     Mahta A, Kesari S*. The blues of minocycline. QJM 2011; (epub)
*Senior/corresponding author

35.     Mahta A, Kesari S*. The greens of lead. QJM 2012;105(12):1223.
*Senior/corresponding author

36.     Mahta A, Borys E, Kanakamedala MR, Kesari S*. Radiation induced myelopathy in a patient with tongue cancer. Acta Oncol 2012;51(3):409-11.
*Senior/corresponding author

37.     Mahta A, Kim RY, Kesari S*. Levetiracetam-induced interstitial nephritis in a patient with glioma. J Clin Neuroscience 2012;19(1):177-8.
*Senior/corresponding author

38.     Li JC, Mahta A, Kim RY, Saria M, Kesari S*. Cerebral syphilitic gumma: a case report and review of the literature. 2012;33(5):1179-81.

*Senior/corresponding author

39.     Cai P, Mahta A, Kim RY, Kesari S*. Paraganglioma with intracranial metastasis: A case report and review of the literature. Neurol Sci 2012;33(5):1183-4.
*Senior/corresponding author

40.     Kanakamedala MR, Mahta A, Liu J, Kesari S*. Late temporal lobe necrosis after conventional radiotherapy for carcinoma of maxillary sinus. Med Oncol 2012;29(4):2456-8.
*Senior/corresponding author

41.     Mahta A, Hu A, Kim RY, Kesari S*. Decompensated chronic congenital hydrocephalus. 2011; 111(4):373.
*Senior/corresponding author

42.     Fan X, Mahta A, De Jager PL, Kesari S*. Rituximab for tumefactive inflammatory demyelination: A case report. Clin Neurol Neurosurg 2012;114(10):1326-8.
*Senior/corresponding author

43.     Lin N, Huttner A, Spieler P, Claus EB, Kesari S*. 55-year-old female with low back pain. Brain Pathology 2012;22(3):427-8.
*Senior/corresponding author

44.     Mahta A, Buhl R, Huang H, Jansen O, Kesari S, Ulmer S. Sellar and supra-sellar glioblastoma masquerading as a pituitary macroadenoma. Neurological Sciences 2012; (epub)

45.     Imitola J, Pitt K, Peoples JL, Krynska B, Sheikh H, Kesari S, Azizi SA. Multifocal CNS infiltration of chronic lymphocytic leukemia in the form of small-cell solid metastatic disease. Journal of Neuro-Oncology 2012;109(1):213-15.

46.     Rosenberg J, Mahta A, Koppula K, Borys E, Kesari S*. Cyclophosphamide responsive primary angiitis of the CNS in a 61-year-old female. Clin Neuropath 2012; (epub)
*Senior/corresponding author

47.     Srinivasan S, Mahta A, Kesari S*. Cardioembolic stroke following a fractured transeptal wire. QJM 2012; (epub)
*Senior/corresponding author

48.     Mahta A, Du Z, Borys E, Carter B, Vandenberg SR, Kesari S*. 78-year-old male with dysphagia and dysarthria. Brain Pathology. Brain Pathology 2013; (epub)
*Senior/corresponding author

49.     Mahta A, Hu S, Borys E, Vandenberg SR, Carter B, Kesari S*. 72-year-old female with leg weakness. Brain Pathology 2013; (epub)
*Senior/corresponding author

CLINCAL  COMMUNICATIONS

1.         Kesari S.  Digitally altered photographs depicting different manifestations of visual aura. In: Merck & Co. Monographs in Medicine: A Study of Migraine. New Jersey: Whitehouse Station; 2005. p. 38.

2.         Norden AD, Kesari S. Cancer neurology: Primary and metastatic brain tumors. In: Atri A, Milligan TA, editors. Hospital physician neurology board review manual. Wayne (PA): Turner White Communications; 2006:10(Pt 3):1-16.

3.         Norden AD, Kesari S. Cancer neurology: Primary CNS lymphoma, paraneoplastic syndromes, and pituitary adenoma. In: Atri A, Milligan TA, editors. Hospital physician neurology board review manual. Wayne (PA): Turner White Communications; 2007:11(Pt 1):1-16.

4.         Schiff D, Kesari S, Wen PY (eds). Cancer Neurology in Clinical Practice. 2nd edition. Humana Press Totowa, NJ 2008.

5.         Focusing on Tumors: Meningiomas: Saria M, Kesari S (eds). Published by the American Brain Tumor Association, 2011.

6.         Grewal J, Grewal HK, Kesari S. Primary brain tumors. In: Skarin A, editor. Hospital physician oncology board review manual. Wayne (PA): Turner White Communications; 2013:13(Pt x):.

 7.         Grewal J, Grewal HK, Kesari S. Metastatic brain tumors. In: Skarin A, editor. Hospital physician oncology board review manual. Wayne (PA): Turner White Communications; 2013:13(Pt x):.

BOOKS, MONOGRAPHS AND TEXTBOOKS

1.         Trojanowski JQ, Kleppner SR, Hartley RS, Miyazono M, Fraser NW, Kesari S, Lee VM.  Transfectable and transplantable postmitotic human neurons: A potential "platform" for gene therapy of nervous system diseases. Experimental Neurology 1997;144(1):92-7.

2.         Kesari S, Batchelor T. Leptomeningeal metastasis. Neurologic Clinics 2003;21(1):25-66.

3.         Wen PY, Kesari S.  Neurologic complications of chemotherapy. In: Gilman S, editor. MedLink Neurology. San Diego: MedLink Corporation. Available at www.medlink.com. Accessed April 1, 2003.

4.         Kesari S.  Paraneoplastic neurologic syndromes in women's cancer [review].  J Watch Neurol. October 2003. Review of Rojas-Marcos I et al. Spectrum of paraneoplastic neurologic disorders in women with breast and gynecologic cancer.  Medicine 2003;May;82:216-23.

5.         Kesari S.  Update on paraneoplastic neurological syndromes [review].  J Watch Neurol. February 2004. Review of Darnell & Posner, Paraneoplastic neurologic syndromes.  NEJM 2003; Oct­;349(16):1543-54.

6.         Kesari S, Wen PY. Neurooncology. In: Samuels M, editor. Manual of Neurologic Therapeutics, 7th edition, Philadelphia: Lippincott Williams & Wilkins; 2004. p. 115-178.

7.         Wen PY, Kesari S. Malignant gliomas. Current Neurology and Neuroscience Reports 2004;4(3):218-27.

8.         Wen PY, Kesari S, Hsu L, De Girolami U.  Brain Tumors. In: Griggs RC, Joynt RJ. editors. Baker and Joynt’s Clinical Neurology CD-ROM, Philadelphia: Lippincott Williams & Wilkins; 2004.

9.         Mrugala MM, Kesari S, Ramakrishna N, Wen PY. Therapy for recurrent malignant gliomas.  Expert Review of Anticancer Therapy 2004;4(5):759-82.

10.     Kesari S, Wen PY.  Neuroprotective effect of vitamin E supplementation [commentary]. Neurology. January 11, 2005; Commentary on Argyriou et al., Vitamin E For Prophylaxis Against Chemotherapy-Induced Neuropathy: A Randomised Controlled Trial. Neurology 2005 Jan;64:26-31.

11.     Kesari S, Ramakrishna N, Sauvageot C, Stiles CD, Wen PY. Targeted molecular therapy of malignant gliomas. Current Neurology and Neuroscience Reports 2005;5(3):186-97.

12.     Norden AD, Kesari S.  Pituitary adenoma. In: Gilman S, editor. MedLink Neurology. San Diego: MedLink Corporation. Available at www.medlink.com. Accessed November 11, 2005.

13.     Norden AD, Wen PY, Kesari S*. Brain metastases. Current Opinion in Neurology 2005;18(6):654-61.
*Senior/corresponding author

14.     Kesari S, Ramakrishna N, Sauvageot C, Stiles CD, Wen PY. Targeted molecular therapy of malignant gliomas. Current Oncology Reports 2006;8(1):58-70.

15.     Chi, A, Kesari S.  POEMS syndrome. In: Gilman S, editor. MedLink Neurology. San Diego: MedLink Corporation. Available at www.medlink.com. Accessed February 1, 2006.

16.     Wen PY, Kesari S, Drappatz J. Malignant gliomas: Strategies to increase the effectiveness of targeted molecular treatment.  Expert Review of Anticancer Therapy 2006;6(5):733-54.

17.     Kesari S, Santagata S.  Germinoma. In: Gilman S, editor. MedLink Neurology. San Diego: MedLink Corporation. Available at www.medlink.com. Accessed March 29, 2006.

18.     Wen PY, Kesari S, Grier J. Neurologic complications of chemotherapy. In: Gilman S, editor. MedLink Neurology. San Diego: MedLink Corporation. Available at www.medlink.com. Accessed June 15, 2006.

19.     Wen PY, Schiff D, Kesari S, Drappatz J, Gigas DC, Doherty L. Medical management of patients with brain tumors.  Journal of Neuro-Oncology 2006;80(3):313-32.

20.     Kesari S, Stiles CD. The Bad Seed: PDGF receptors link adult neural progenitors to glioma stem cells. Neuron 2006;51(2):151-3.

21.     Quant E, Kesari S. Primary central nervous system lymphoma. In: Gilman S, editor. MedLink Neurology. San Diego: MedLink Corporation. Available at www.medlink.com. Accessed August 13, 2006.

22.     Monje M, Kesari S. Sequelae of treatments of CNS tumors. In: Gilman S, editor. MedLink Neurology. San Diego: MedLink Corporation. Available at www.medlink.com. Accessed December 4, 2006.

23.     Norden AD, Kesari S. Pituitary adenoma. In: Gilman S, editor. MedLink Neurology. San Diego: MedLink Corporation. Available at www.medlink.com. Accessed December 10, 2006.

24.     Chheda M, Kesari S, Wen PY. Uncommon Brain Tumors. In: Rose B (editor), UptoDate, Waltham, MA: UpToDate. Available at www.uptodate.com, Accessed January 4, 2007. 

25.     Kesari S, Santagata S.  Germinoma. In: Gilman S, editor. MedLink Neurology. San Diego: MedLink Corporation. Available at www.medlink.com. Accessed January 20, 2007.

26.     Kesari S, Jackson-Grusby L, Stiles CD. ‘Smad’eningly erratic: target gene methylation determines whether TGFb promotes or suppresses malignant glioma. Developmental Cell 2007;12(3):324-5.

27.     Kesari S. Low-Grade Gliomas: Natural History and Chemotherapy Response [review].  J Watch Neurol. July 31, 2007. Review of Ricard D, et al, Dynamic history of low-grade gliomas before and after temozolomide treatment.  Ann Neurol 2007;61:484-90.

28.     Sauvageot CM. Kesari S, Stiles CD.  Molecular pathogenesis of adult brain tumors and the role of stem cells. Neurologic Clinics 2007;25(4):891-924.

29.     Drappatz J, Schiff D, Kesari S, Norden AD, Wen PY.  Medical management of brain tumor patients. Neurologic Clinics 2007;25(4):1035-71.

30.     Grewal J, Kesari S. Breast cancer surface receptors predict risk of developing brain metastasis and subsequent prognosis [editorial]. Breast Cancer Research 2008;10(2):104.

31.     Kesari S, Paleologos N, Vick N.  Corticosteriods in neuro-oncology. In: Cancer Neurology in Clinical Practice: Neurologic Complications of Cancer and its Treatment. 2nd edition. Schiff D, Kesari S, Wen PY, (ed) Totowa, New Jersey. Humana Press 2008, 47-56.

32.     Kesari S, Kunschner LJ.  Neurological complications of sarcoma. In: Cancer Neurology in Clinical Practice: Neurologic Complications of Cancer and its Treatment. 2nd edition. Schiff D, Kesari S, Wen PY (ed) Totowa, New Jersey. Humana Press 2008, 495-506.

33.     Dietrich J, Imitola J, Kesari S.  Mechanisms of disease: the role of stem cells in the biology and treatment of gliomas. Nature Clinical Practice Oncology 2008;5(7):393-404.

34.     Kesari S. Meningitis in Cancer Patients: Changes Accompany Medical Advances. [review].  J Watch Neurol. August 31, 2008. Review of Safdieh JE, et al. Bacterial and fungal meningitis in patients with cancer. Neurology 2008 Mar 18;70:943-7.

35.     Wen PY, Kesari S.  Malignant gliomas in adults. New England Journal of Medicine 2008;359(5):492-507.

36.     Grewal J, Grewal HK, Kesari S. Brain Tumors. In: Neurology review for psychiatrists. Savitz SI and Ronthal M (eds). Lippincott Williams & Wilkins. 2009, 283-304.

37.     Kesari S. A novel target for glioblastoma therapy. [review].  J Watch Neurol. July 31, 2009. Review of Yan H, et al. IDH1 and IDH2 mutations in gliomas. New England Journal of Medicine 2009 Feb 19;360:765-73.

38.     Glantz M, Kesari S, Recht L, Fleischhack G, Van Horn A. Understanding the origins of gliomas and developing novel therapies: Cerebrospinal fluid and subventricular zone interplay. Seminars in Oncology 2009; 36(4 Suppl 2):S17-24.

39.     Grewal J, Grewal HK, Kesari S. POEMS syndrome. In: Gilman S, editor. MedLink Neurology. San Diego: MedLink Corporation. Available at www.medlink.com. Accessed September 14, 2009.

40.     Grewal J, Duic JP, Kesari S. Spinal ependymoma. In: Gilman S, editor. MedLink Neurology. San Diego: MedLink Corporation. Available at www.medlink.com. Accessed September 15, 2009.

41.     Duic JP, Grewal J, Kesari S. Germinoma. In: Gilman S, editor. MedLink Neurology. San Diego: MedLink Corporation. Available at www.medlink.com. Accessed September 16, 2009.

42.     Dietrich J, Kesari S. Effect of cancer treatment on neural stem and progenitor cells. In: Late Effects of Treatment for Brain Tumors. Goldman S and Turner CD (eds). Cancer Treat Res 2009;150:81-95.

43.     Grewal J, Tessler L, Kesari S. Pituitary adenoma. In: Gilman S, editor. MedLink Neurology. San Diego: MedLink Corporation. Available at www.medlink.com. Accessed October 28, 2009.

44.     Kesari S. Acute headache. In: Mushlin S, Greene HL (eds). Decision making in medicine: An algorithmic approach. 3rd ed. St. Louis: Mosby; 2010. 402-3.

45.     Kesari S. Chronic headache. In: Mushlin S, Greene HL (eds). Decision making in medicine: An algorithmic approach. 3rd ed. St. Louis: Mosby; 2010. 403-7.

46.     Kesari S. Disturbances of smell and taste. In: Mushlin S, Greene HL (eds). Decision making in medicine: An algorithmic approach. 3rd ed. St. Louis: Mosby; 2010. p. 458-9.

47.     Dietrich J, Diamond EL, Kesari S*. Glioma stem cell signaling: Therapeutic opportunities and challenges. Expert Review of Anticancer Therapy 2010;10(5):709-22.

48.     Saar BG, Freudiger CW, Xu X, Huttner A, Kesari S, Young G, Xie XS. Coherent Raman Tissue Imaging in the Brain. Cold Spring Harbor article 2010;

49.     Dunbar EM, Kesari S. Tubular Vasculogenic Mimicry in Glioblastoma: Glioblastoma cells can make their own blood vessels. [summary and comment].  J Watch Neurol. December 2010. Review of El Hallani S, et al, A new alternative mechanism in glioblastoma vascularization: Tubular vasculogenic mimicry.  Brain 2010;133:973.

50.     Dunbar EM, Kesari S. Low-grade Gliomas in Older Patients: Older adults have inferior outcomes compared with younger adults. [summary and comment].  J Watch Neurol. December 2010. Review of Kaloshi G, et al, Supratentorial low-grade gliomas in older patients.  Neurology 2009;73:2093.

51.     Dunbar EM, Kesari S*. Gliomas: Current issues in diagnosis and treatment. CMIR 2010; (in press)

52.     Kesari S, Wen PY.  Neurooncology. In: Samuels MA, Ropper A (eds). Samuel’s Manual of Neurologic Therapeutics, 8th edition, Philadelphia: Lippincott Williams & Wilkins; 2010. p. 114-170.

53.     Kesari S, Bota DA. Fos-related antigen-1 (Fra-1) is a regulator of glioma cell malignant phenotype. 2011;11(3):307-10.

54.     Mou X, Kesari S, Wen PY, Huang X. Crude Drugs as Anticancer Agents. Int J Clin Exp Med. 2011;4(1):17-25.

55.     Dietrich J, Rao K, Pastorino S, Kesari S. Corticosteriods in brain cancer patients: benefits and pitfalls. Expert Rev Clin Pharmacol 2011;4(2):233-42.

56.     Corle C, Makale M, Kesari S.  Cell phones and glioma risk: A review of the evidence. J Neuro-oncology. 2012;106(1):1-13.

57.     Grewal J, Saria MG, Kesari S. Novel approaches to treating leptomeningeal metastases. J Neuro-oncology 2011;106(2):225-234.

58.     Ng K, Kim R, Kesari S, Carter B, Chen CC.  Genomic Profiling of glioblastoma: convergence of fundamental biologic tenets and novel insights 2012;107(1):1-2.

59.     Kesari S, Advani SJ, Lawson JD, Kahle KT, Ng K, Carter B, Chen CC.  DNA damage response and repair: Insights into strategies for radiation sensitization of gliomas. Future Oncology 2011;7(11):1335-46.

60.     Kim RY, Mahta A, Kesari S (2011). Glioma stem cells, Cancer Stem Cells-The Cutting Edge, Stanley Shostak (Ed.), ISBN: 978-953-307-580-8, InTech, Available from: http://www.intechopen.com/articles/show/title/glioma-stem-cells      

61.     Ng K, Kesari S, Carter B, Chen CC (2011).  Molecular Etiology of Glioblastomas: Implication of Genomic Profiling From the Cancer Genome Atlas Project, Glioma-Exploring Its Biology and Practical Relevance, Anirban Ghosh (Ed.), ISBN: 978-953-307-379-8, InTech, Available from: http://www.intechopen.com/articles/show/title/molecular-etiology-of-glioblastomas-implication-of-genomic-profiling-from-the-cancer-genome-atlas-pr

62.     Lawson JD, Kahle KT, Ng K, Carter B, Kesari S, Chen CC (2011). DNA Damage Response and Repair: Insights into Strategies for Radiation Sensitization, Selected Topics in DNA Repair, Clark C. Chen (Ed.), ISBN: 978-953-307-606-5, InTech, Available from: http://www.intechopen.com/articles/show/title/dna-damage-response-and-repair-insights-into-strategies-for-radiation-sensitization

63.     Jiri B Jr., Ng K, Jiri B Sr., Kesari S, Carter B, Chen CC (2011). Key Principles in Glioblastoma Therapy. Advances in the Biology, Imaging and Therapies for Glioblastoma, Clark C. Chen (Ed.), ISBN: 978-953-307-284-5, InTech, Available from: http://www.intechopen.com/articles/show/title/key-principles-in-glioblastoma-therap

64.     Kesari S. Understanding Glioblastoma Tumor Biology: the potential to improve current diagnosis and treatments. Seminars in Oncology 2011;38(s4):S2-10.

65.     Hu J, Kesari S. The molecular basis for novel therapies. Cancer J 2012: 18(1):32-9.

66.     Grewal J, Saria M, Grewal HK, Kesari S. Neoplastic meningitis resulting from hematological malignancies: Pharmacokinetic considerations and maximizing outcome. Clin Investig 2011;1(10):1391-1402.

67.     Aenlle L, Dunbar E, Kesari S. Medical management of neurological cancers. In: Jeyaplan S, Kasper E, Mahadevan A (eds). Adult Neuro-oncology: A Multidisciplinary, Evidence-Based Approach with Case Studies. 1st ed. St. Louis: Springer; 2011.

68.     Mahta A, Kesari S. Systemic therapy for cancer of the nervous system. In: Jeyaplan S, Kasper E, Mahadevan A (eds). Adult Neuro-oncology: A Multidisciplinary, Evidence-Based Approach with Case Studies. 1st ed. St. Louis: Springer; 2011.

69.     Cibula J, Kesari S, Dunbar EM. Abnormalities of gait. In: Jeyaplan S, Kasper E, Mahadevan A (eds). Adult Neuro-oncology: A Multidisciplinary, Evidence-Based Approach with Case Studies. 1st ed. St. Louis: Springer; 2011.

70.     Hu J, Kesari S. General aspects of chemotherapy. In: Schiff D (eds). Neuro-oncology. 1st ed. St. Louis: Wiley-Blackwell; 2011.

71.     Dunbar EM, Kalani R, Kesari S.  Neurological complications of corticosteroids in cancer therapy. In: Neurologic Complications of Cancer Therapy. 1st edition. Quant E, Schiff D, Wen PY (eds) City, State. Demos Medical Publishing 2012, xxx.

72.     Hu J, Kesari S. Strategies for overcoming the blood-brain barrier for the treatment of brain metastases. CNS Oncology 2013;2(1):87-98.

 73.     Scott BJ, Kesari S. Leptomeningeal Metastases in Breast Cancer. American Journal of Cancer Research. 2013 (in press).

RREVIEWS, CHAPTERS AND EDITORIALS

1.         Randazzo BP, Kesari S, Gesser RM, Alsop D, Ford JC, Brown SM, MacLean AR, Fraser NW. Treatment of experimental intracranial murine melanoma with a neuroattenuated herpes simplex virus 1 mutant. Virology 1995;211(1):94-101.

2.         Kesari S, Randazzo BP, Nagy T, Huang QS, Brown SM, MacLean AR, Lee VM, Trojanowski JQ, Fraser NW. Therapy of experimental human brain tumors using a neuroattenuated herpes simplex virus mutant. Laboratory Investigation 1995;73(5):636-48.

3.         Kesari S, Lee VM, Brown SM, Trojanowski JQ, Fraser NW. Selective vulnerability of mouse CNS neurons to latent infection with a neuroattenuated herpes simplex virus-1. Journal of Neuroscience 1996;16(18):5644-53.

4.         Lasner TM, Kesari S, Brown SM, Lee VM, Fraser NW, Trojanowski JQ. Therapy of a murine model of pediatric brain tumors using a herpes simplex virus type-1 ICP34.5 mutant and demonstration of viral replication within the CNS. Journal of Neuropathology and Experimental Neurology 1996;55(12):1259-69.

5.         Wolfe JH, Martin CE, Deshmane SL, Reilly JJ, Kesari S, Fraser NW. Increased susceptibility to the pathogenic effects of wild-type and recombinant herpesviruses in MPS VII mice compared to normal siblings. Journal of Neurovirology 1996;2(6):417-22.

6.         Randazzo BP, Bhat MG, Kesari S, Fraser NW, Brown SM. Treatment of experimental subcutaneous human melanoma with a replication-restricted herpes simplex virus mutant. Journal of Investigative Dermatology 1997;108(6):933-7.

7.         Huang QS, Nagy T, Kesari S, Fraser NW. Beta-gal enzyme activity driven by the HSV LAT promoter does not correspond to Beta-gal RNA levels in mouse trigeminal ganglia. Gene Therapy 1997;4(8):797-807.

8.         Randazzo BP, Tal-Singer R, Zabolotny JM, Kesari S, Fraser NW.  Herpes simplex virus 1716, an ICP 34.5 null mutant, is unable to replicate in CV-1 cells due to a translational block that can be overcome by coinfection with SV40. Journal of General Virology 1997;78(12):3333-9.

9.         Kesari S, Lasner TM, Balsara KR, Randazzo BP, Lee VM, Trojanowski JQ, Fraser NW. A neuroattenuated ICP34.5-deficient herpes simplex virus type 1 replicates in ependymal cells of the murine central nervous system. Journal of General Virology 1998;79(3):525-36.

10.     Lasner TM, Tal-Singer R, Kesari S, Lee VM, Trojanowski JQ, Fraser NW. Toxicity and neuronal infection of a HSV-1 ICP34.5 mutant in nude mice. Journal of Neurovirology 1998;3(1):100-5.

11.     Springer SL, Vite CH, Polesky AC, Kesari S, Fraser NW, Wolfe JH. Infection and establishment of latency in the dog brain after direct inoculation of a nonpathogenic strain of herpes simplex virus-1. Journal of Neurovirology 2001;7(2):149-54.

12.     Shah GD*, Kesari S*, Xu R, Batchelor TT, O’Neill AM, Hochberg FH, Levy B, Bradshaw J, Wen PY. Comparison of linear and volumetric criteria in assessing tumor response in adult high-grade gliomas. Neuro-Oncology 2006;8(1):38-46.
*Co-First Authors

13.     Ligon KL, Kesari S, Kitada M, Sun T, Arnett HA, Alberta JA, Anderson DJ, Stiles CD, Rowitch DH. Development of NG2 neural progenitor cells requires Olig gene function. Proceedings of the National Academy of Sciences 2006;103(20):7853-8.

14.     Wüthrich C, Kesari S, Kim WK, Williams K, Gelman R, Elmeric D, De Girolami U, Joseph JT, Hedley-Whyte T, Koralnik IJ. Characterization of lymphocytic infiltrates in progressive multifocal leukoencephalopathy: Co-localization of CD8(+) T cells with JCV-infected glial cells.  Journal of Neurovirology 2006;12(2):116-28.

15.     Doherty L, Gigas DC, Kesari S, Drappatz J, Kim R, Zimmerman J, Ostrowsky L, Wen PY.  Pilot study of the combination of EGFR and mTOR inhibitors in recurrent malignant gliomas. Neurology 2006;67(1):156-8.

16.     Jackman DM, Holmes AJ, Lindeman N, Wen PY, Kesari S, Borras AM, Bailey C, de Jong F, Jänne PA, Johnson BE. Response and resistance in a non-small-cell lung cancer patient with an epidermal growth factor receptor mutation and leptomeningeal metastases treated with high-dose gefitinib. Journal of Clinical Oncology 2006;24(27):4517-20.

17.     Khwaja FW, Reed MS, Olson JJ, Schmotzer BJ, Gillespie GY, Guha A, Groves MD, Kesari S, Pohl J, Van Meir EG. Proteomic identification of biomarkers in the cerebrospinal fluid (CSF) of astrocytoma patients. Journal of Proteome Research 2007;6(2):559-70.

18.     Ligon KL, Huillard E, Mehta S, Kesari S, Liu H, Alberta JA, Bachoo RM, Kane M, Louis DN, DePinho RA, Anderson DJ, Stiles CD, Rowitch DH. Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma. Neuron 2007;53(4):503-17.

19.     Kesari S, Schiff D, Doherty L, Gigas DC, Batchelor TT, Muzikansky A, O’Neill A, Drappatz J, Chen-Plotkin AS, Ramakrishna N, Weiss SE, Levy B, Bradshaw J, Kracher J, Laforme A, Black PM, Folkman J, Kieran M, Wen PY. Phase II study of metronomic chemotherapy for recurrent malignant gliomas in adults.  Neuro-Oncology 2007;9(3): 354-63.

20.     Evans CL, Xu X, Kesari S, Xie XS, Wong ST, Young GS. Chemically-selective imaging of brain structures with CARS microscopy. Optics Express 2007;15(19):12076-87.

21.     Norden AD, Young GS, Setayesh K, Muzikansky A, Kulfas R, Ross GL, Ciampa AS, Ebbeling LG, Levy B, Drappatz J, Kesari S, Wen PY. Bevacizumab for recurrent malignant gliomas:  Efficacy, toxicity, and patterns of recurrence. Neurology 2008;70(10):779-87.

22.     Kesari S*, Kim RS, Markos V, Drappatz J, Wen PY, Pruitt AA. Prognostic factors in adult brainstem gliomas: A multicenter, retrospective analysis of 101 cases.  Journal of Neuro-Oncology 2008;88(2):175-83.
*Senior/corresponding author

23.     Kesari S, Schiff D, Henson JW, Muzikansky A, Gigas DC, Doherty L, Batchelor TT, Longtine JA, Ligon KL, Weaver S, Laforme A, Ramakrishna N, Black PM, Drappatz J, Ciampa A, Folkman J, Kieran M, Wen PY. Phase II study of temozolomide, thalidomide, and celecoxib for newly diagnosed glioblastoma in adults. Neuro-Oncology 2008;10(3):300-8.

24.     Drappatz J, Wong ET, Schiff D, Kesari S, Batchelor TT, Doherty L, LaFrankie DC, Ramakrishna N, Weiss S, Smith ST, Ciampa A, Zimmerman J, Ostrowsky L, David K, Norden A, Barron L, Sceppa C, Black PM, Wen PY. A pilot safety study of lenalidomide and radiotherapy for patients with newly diagnosed glioblastoma multiforme. International Journal of Radiation Oncology Biology Physics 2009;73(1):222-7. Epub 2008 May 29.

25.     Lee JW, Bromfield EB, Kesari S*.  Emesis responsive to levetiracetam. Journal of Neurology, Neurosurgery, and Psychiatry 2008;79(7):847-9.
*Senior/corresponding author

26.     Gabriely G, Wurdinger T, Kesari S, Esau CC, Burchard J, Linsley PS, Krichevsky AM.  MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators.  Molecular and Cellular Biology 2008;28(17):5369-80.

27.     Musunuru K, Kesari S*. Paraneoplastic opsoclonus-myoclonus ataxia associated with non-small-cell lung carcinoma. Journal of Neuro-Oncology 2008; 90(2):213-6.
*Senior/corresponding author

28.     Kesari S*, Akar S, Saad A, Drappatz J, Koralnik I, DeAngelo DJ. Progressive multifocal leukoencephalopathy in a patient with relapsed acute myelogenous leukemia. Journal of Clinical Oncology 2008;26(22):3804-7.
*Senior/corresponding author

29.     Stegh AH, Kesari S, Mahoney JE, Jenq HT, Forloney KL, Protopopov A, Louis DN, Chin L, DePinho RA. Bcl2L12-mediated inhibition of effector caspase-3 and caspase-7 via distinct mechanisms in glioblastoma. Proceedings of the National Academy of Sciences 2008;105(31):10703-8.

30.     Ziegler DS, Wright RD, Kesari S, Lemieux ME, Tran MA, Jain M, Zawel L, Kung AL. Resistance of human glioblastoma multiforme cells to growth factor inhibitors is overcome by blockade of inhibitor of apoptosis proteins. Journal of Clinical Investigation 2008;118(9):3109-22.

31.     Sauvageot CM, Weatherbee JL, Kesari S, Winters SE, Barnes J, Dellagatta J, Ramakrishna NR, Stiles CD, Kung AL, Kieran MW, Wen PY. Efficacy of the HSP90 inhibitor 17-AAG in human glioma cell lines and tumorigenic glioma stem cells. Neuro-Oncology 2009;11(2):109-21.

32.     Norden AD, Drappatz J, Ciampa AS, Doherty L, LaFrankie DC, Kesari S, Wen PY. Colon perforation during anti-angiogenic therapy for malignant glioma. Neuro-Oncology 2009;11(1):92-5.

33.     Bracht LK, Wen P, Meyerhardt JA, Kulke MH, Hornick JL, Redston M, LaFrankie DC, Black PM, Kesari S, Norden A, Drappatz J. DNA repair enzyme expression and differential response to temozolomide in a patient with both glioblastoma and metastatic pancreatic neuroendocrine tumor. Journal of Clinical Oncology 2008;26(29):4843-4.

34.     Ulmer S, Liess C, Kesari S, Otto N, Straube T, Jansen O. Use of dynamic susceptibility-contrast MRI (DSC-MRI) to assess perfusion changes in the ipsilateral brain parenchyma from glioblastoma. Journal of Neuro-Oncology 2009;91(2):213-20. Epub 2008 Sep 21.

35.     Lee JW, Bromfield EB, Kesari S*. Antiemetic properties of the antiepileptic drug levetiracetam. New England Journal of Medicine 2008;359(17):1853.
*Senior/corresponding author

36.     Norden AD, Drappatz J, Muzikansky A, David K, Gerard M, McNamara MB, Phan P, Ross A, Kesari S, Wen PY. An exploratory survival analysis of anti-angiogenic therapy for recurrent malignant glioma. Journal of Neuro-Oncology 2009;92(2):149-55.

37.     Wüthrich C, Cheng YM, Joseph JT, Kesari S, Beckwith C, Stopa E, Bell JE, Koralnik IJ. Frequent infection of cerebellar granule cell neurons by polyomavirus JC in progressive multifocal leukoencephalopathy. Journal of Neuropathology and Experimental Neurology 2009;68(1):15-25.

38.     Kolesnikova TV, Kazarov AR, Lemieux ME, Lafleur MA, Kesari S, Kung AL, Hemler ME. Glioblastoma inhibition by cell surface immunoglobulin protein EWI-2, in vitro and in vivo. Neoplasia 2009;11(1):77-86.

39.     Ng K, Nitta M, Hu L, Kesari S, Kung A, D’Andrea A, Chen CC. A small interference RNA screen revealed proteasome inhibition as strategy for glioblastoma therapy. Clinical Neurosurgery 2009;56:107-18.

40.     Kesari S, Schiff D, Drappatz J, LaFrankie D, Doherty L, Macklin EA, Muzikansky A, Santagata S, Ligon KL, Norden AD, Ciampa A, Bradshaw J, Levy B, Radakovic G, Ramakrishna N, Black PM, Wen PY. Phase II study of protracted daily temozolomide for low-grade gliomas in adults. Clinical Cancer Research 2009;15(1):330-7.

41.     Wen PY, Yung WK, Lamborn KR, Norden AD, Cloughesy TF, Abrey LE, Fine HA, Chang SM, Robins HI, Fink K, , DeAngelis LM, Mehta M, Di Tomaso E, Drappatz J, Kesari S, Ligon KL, Aldape K, Jain RK, Stiles CD, Egorin MJ, Prados MD.  Phase II study of imatinib mesylate for recurrent meningiomas (North American Brain Tumor Consortium Study 01-08). Neuro-Oncology 2009;11(6):853-60.

42.     Quant EC, Norden AD, Drappatz J, Muzikansky A, Doherty L, LaFrankie D, Ciampa A, Kesari S, Wen PY. Role of a second chemotherapy in recurrent malignant glioma patients who progress on bevacizumab. Neuro-Oncology 2009;11(5):550-5.

43.     Wakimoto H, Kesari S, Farrell CJ, Curry WT Jr, Zaupa C, Aghi M, Kuroda T, Stemmer-Rachamimov A, Shah K, Liu TC, Jeyaretna DS, Debasitis J, Pruszak J, Martuza RL, Rabkin SD.  Human glioblastoma-derived cancer stem cells: Establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors. Cancer Research 2009;69(8):3472-81                                                                                                                                         
44.     Zhao H, Zhu J, Cui K, Xu X, O’Brien M, Wong KK, Kesari S, Xia W, Wong ST.  Bioluminescence imaging reveals inhibition of tumor cell proliferation by Alzheimer’s amyloid beta protein. Cancer Cell International 2009;9:15.

45.     Richardson PG, Xie W, Mitsiades C, Chanan-Khan AA, Lonial S, Hassoun H, Avigan DE, Oaklander AL, Kuter DJ, Wen PY, Kesari S, Briemberg HR, Schlossman RL, Munshi NC, Heffner LT, Doss D, Esseltine D, Weller E, Anderson KC, Amato AA. Single-agent bortezomib in previously untreated multiple myeloma: efficacy, characterization of peripheral neuropathy, and molecular correlates with response and neuropathy. Journal of Clinical Oncology 2009;27(21):3518-25.

46.     Pfeffer MA, Burdmann EA, Chen CY, Cooper ME, de Zeeuw D, Eckardt KU, Feyzi JM, Ivanovich P, Kewalramani R, Levey AS, Lewis EF, McGill JB, McMurray JJ, Parfrey P, Parving Hh, Remuzzi G, Singh AK, Solomon SD, Toto R, TREAT Investigators (Kesari S). A trial of darbepoetin alfa in type 2 diabetes and chronic kidney disease. New England Journal of Medicine 2009;361(21):2019-32.

47.     Marzocchetti A, Tompkins T, Clifford DB, Gandhi RT, Kesari S, Berger JR, Simpson DM, Prosperi M, De Luca A, Koralnik IJ. Determinants of survival in progressive multifocal leukoencephalopathy. Neurology 2009;73(19):1551-8.

48.     Grewal J, Zhou H, Factor R, Kesari S*. Isolated loss of hormonal receptors in leptomeningeal metastasis from estrogen receptor- and progesterone receptor-positive lobular breast cancer. Journal of Clinical Oncology 2010;28(13):e200-2.
*Senior/corresponding author

49.     Drappatz J, Norden AD, Wong ET, Doherty LM, LaFrankie DC, Ciampa A, Kesari S, Sceppa C, Gerard M, Phan P, Schiff D, Batchelor TT, Ligon KL, Young G, Muzikansky A, Weiss SE, Wen PY.  Phase I study of vandetanib with radiotherapy and temozolomide for newly-diagnosed glioblastoma. International Journal of Radiation Oncology Biology Physics 2010;78(1):85-90.

50.     Zeng Q, Yang Z, Gao Y, Yuan H, Cui K, Shi Y, Wang Y, Huang X, Wong ST, Wang Y, Kesari S, Ji RR, Xu X. Treating triple-negative breast cancer by a combination of rapamycin and cyclophosphamide: an in vivo bioluminescence imaging study. European Journal of Cancer 2010;46(6):1132-43.

51.     Lee JW, Wen PY, Hurwitz S, Black P, Kesari S, Drappatz J, Golby AJ, Wells WM 3rd, Warfield SK, Kikinis R, Bromfield EB. Morphological characteristics of brain tumors causing seizures. Archives of Neurology 2010;67(3):336-42.

52.     Nitta M, Kozono D, Kennedy R, Stommel J, Ng K, Zinn PO, Kushwaha D, Kesari S, Inda MD, Wykosky J, Furnari F, Hoadley KA, Chin L, DePinho RA, Cavenee WK, D’Andrea A, Chen CC. Targeting EGFR induced oxidative stress by PARP1 inhibition in glioblastoma therapy. PLoS One 2010;5(5):e10767.

53.     Nghiemphu PL, Wen PY, Lamborn KR, Drappatz J, Robins HI, Fink K, Malkin MG, Lieberman FS, DeAngelis LM, Torres-Trejo A, Chang SM, Abrey L, Fine HA, Demopoulos A, Lassman AB, Kesari S, Mehta MP, Prados MD, Cloughesy TF; North American Brain Tumor Consortium. A phase I study of tipifarnib with radiation therapy, with and without temozolomide, for patients with newly diagnosed glioblastoma. International Journal of Radiation Oncology Biology Physics 2011;81(5):1422-7.

54.     Chen J*, Kesari S*, Rooney C, Strack PR, Chen J, Shen H, Wu L, Griffin JD. Inhibition of notch signaling blocks growth of glioblastoma cell lines and tumor neurospheres. Genes and Cancer 2010;1(8):822-35.
*Co-First Authors

55.     Young GS, Macklin EA, Setayesh K, Lawson JD, Wen PY, Norden AD, Drappatz J, Kesari S*. Longitudinal MRI evidence for decreased survival among periventricular glioblastomas. J Neuro-Oncology 2011;104(1):261-9.
*Senior/corresponding author

56.     Erten A, Hall D, Hoh C, Tran Cao HS, Kaushal S, Esener S, Hoffman RM, Bouvet M, Chen J, Kesari S, Makale M. Enhancing magnetic resonance imaging tumor detection with fluorescence intensity and lifetime imaging. J Biomed Opt 2010;15(6):066012.

57.     Wong K, Young GS, Makale M, Hu X, Yildirim N, Cui K, Wong ST, Kesari S*. Characterization of a human tumorsphere glioma orthotopic model using magnetic resonance imaging. J Neuro-Oncology 2011;104(2):473-81.
*Senior/corresponding author

58.     Chaponis D, Barnes JW, Dellagatta JL, Kesari S, Fast E, Sauvageot C, Panagrahy D, Greene ER, Ramakrishna N, Wen PY, Kung AL, Stiles C, Kieran MW. Lonafarnib (SCH66336) improves the activity of temozolomide and radiation for orthotopic malignant gliomas. J Neuro-Oncology 2011;104(1):179-89.

59.     Soda Y, Marumoto T, Friedmann-Morvinski D, Soda M, Liu F, Michiue H, Pastorino S, Yang M, Hoffman RM, Kesari S, Verma IM. Transdifferentiation of glioblastoma cells into vascular endothelial cells. Proc Natl Acad Sci 2011;108(11):4274-80.

60.     Mehta S, Huillard E, Kesari S, Maire CL, Golebiowski D, Harrington EP, Alberta JA, Kane MF, Theisen M, Ligon KL, Rowitch DH, Stiles CD. The Central Nervous System-Restricted Transcription Factor Olig2 Opposes p53 Responses to Genotoxic Damage in Neural Progenitors and Malignant Glioma. Cancer Cell 2011;19(3):359-71.

61.     Agnihotri S, Wolf A, Munoz DM, Smith CJ, Gajadhar A, Restrepo A, Clarke ID, Fuller GN, Kesari S, Dirks PB, McGlade CJ, Stanford WL, Aldape K, Mischel PS, Hawkins C, Guha A. A GATA4-Regulated Tumor Suppressor Network Represses Formation of Malignant Human Astrocytoma. J Exp Medicine 2011;208(4):689-702.

62.     Gabriely G, Yi, M, Narayan RS, Niers JM, Wurdinger T, Imitola J, Ligon KL, Kesari S, Esau C, Stephens RM, Tannous BA, Krichevsky AM.  Human glioma growth is controlled by microRNA-10b. Cancer Research 2011;71(10):3563-72.

63.     Gheuens S, Bord E, Kesari S, Simpson DM, Gandhi RT, Clifford DB, Berger JR, Ngo L, Koralnik IJ. Role of CD4+ and CD8+ T-Cell responses against JC virus in the outcome of patients with progressive multifocal leukoencephalopathy (PML) and PML with immune reconstitution inflammatory syndrome. J Virology 2011;85(14):7256-63.

64.     Larman HB, Zhao J, Laserson U, Li MZ, Ciccia A, Gakidis MA, Church GM, Kesari S, LeProust EM, Solimini NL, Elledge SJ. Autoantigen discovery with a synthetic human peptidome. Nature Biotechnology 2011;29(6):535-41.

65.     Yu-Chang L, Kesari S, Bing L, Ya-Suo D, Ming-Zhi P. Individual management of recurrent intracranial aneurysms: The Wuxi Experience. Cell Biochem Biophys 2011;61(2):349-54.

66.     Lin N, Dunn IF, Glantz M, Allison DL, Jensen R, Johnson MD, Friedlander RM, Kesari S*. Benefit of ventriculoperitoneal cerebrospinal fluid shunting and intrathecal chemotherapy in neoplastic meningitis: a retrospective, case-controlled study. J Neurosurgery 2011;115(4):730-6.
*Senior/corresponding author

67.     Ziegler DS, Keating J, Kesari S, Fast EM, Zawel L, Ramakrishna N, Barnes J, Kiernan MW, Veldhuijzen van Zanten SE, Kung AL. A small molecule IAP inhibitor overcomes resistance to cytotoxic therapies in malignant gliomas in vitro and in vivo. Neuro-Oncology 2011;13(8):820-9.

68.     Mukthavaram R, Wrasidlo W, Hall D, Kesari S*, Makale M. Assembly and targeting of liposomal nanoparticles encapsulating quantum dots. Bioconjugate Chemistry 2011;22(8):1638-44.
*Co-Senior/corresponding author

69.     Cho J, Pastorino S, Zeng Q, Xu X, Johnson W, Vandenberg S, Verhaak R, Cherniack A, Watanabe H, Dutt A, Chao YS, Onofrio RC, Rooney C, Chiang D, Yuza Y, Kesari S*, Meyerson M. Glioblastoma-derived epidermal growth factor receptor carboxyl-terminal deletion mutants are transforming and are sensitive to EGFR-directed therapies. Cancer Research 2011 Dec 15;71(24):7587-96. Epub 2011 Oct 14.
*Co-Senior/corresponding author

70.     Santagata S, Xu YM, Wijeratne EM, Kontnik R, Rooney C, Perley CC, Kwon H, Clardy J, Kesari S, Whitesell L, Lindquist S, Gunatilaka AA. Using the Heat-Shock Response to Discover Anticancer Compounds that Target Protein Homeostasis. ACS Chemical Biology 2012;7(2):340-9.

71.     Pan H, Alksne J, Mundt AJ, Murphy KT, Cornell M, Kesari S*, Lawson JD. Patterns of Imaging Failures in Glioblastoma Patients Treated with Chemoradiation: A Retrospective Study. Medical Oncology 2012;29(3):2040-5.
*Co-Senior/corresponding author

72.     Erten A, Makale M, Lu X, Serra V, Fruhberger B, Kesari S, Esener S. Streamlined cryogenic deep reactive ion etching protocol for hybrid micronozzle arrays. J. Micromech. Microeng 2011; (in press).

73.     Fu H, Kesari S, Cai J. Tcf712 is Tightly Controlled During Myelin Formation. Cell Mol Neurobiol 2012;32(3):345-52.

74.      Ulmer S, Spalek K, Nabavi A, Schultka S, Mehdorn HM, Kesari S, Dorner L. Temporal changes in magnetic resonance imaging characteristics of Gliadel wafers and of the adjacent brain parenchyma. Neuro-Oncology 2012;14(4):482-90.

75.     Teplyuk NM, Mollenhauer B, Gabriely G, Giese A, Kim E, Smolsky M, Kim RY, Saria MG, Pastorino S, Kesari S*, Krichevsky AM. MicroRNAs in cerebrospinal fluid identify glioblastoma and metastatic brain cancers and reflect disease activity.  Neuro-Oncology, 2012;14(6):689-700.
*C-Senior/corresponding author

76.     Chao Y, Makale M, Karmali PP, Sharikov Y, Tsigelny IF, Merkulov S, Kesari S, Wrasdilo W, Ruoslahti E, Simberg D. Recognition of dextran-superparamagnetic iron oxide nanoparticle conjugates (Feridex) via macrophage scavenger receptor charged domains. Bioconjug Chem. 2012 Apr 19. (Epub)

77.     Krop I, Demuth T, Guthrie T, Wen PY, Mason WP, Chinnaiyan P, Butowski N, Groves MD, Kesari S, Freedman SJ, Blackman S, Watters J, Loboda A, Podtelezhnikov A, Lunceford J, Chen C, Giannotti M, Hing J, Beckman R, LoRusso P. Phase I Pharmacologic and Pharmacodynamic Study of the Gamma Secretase (Notch) inhibitor MK-0752 in Adult Patients with Advanced Solid Tumors. J Clin Oncol 2012;30(19):2307-13.

78.     Elbabaa SK, Gokden M, Crawford JR, Kesari S, Saad AG. Radiation-Associated Meningiomas in Children: Clinical, Pathological and Cytogenetic Characteristics with a Critical Review of the Literature. J Neurosurgery Pediatrics 2012;10(4):281-90.

79.     Freudiger CW, Pfannl R, Orringer DA, Saar BG, Ji M, Zeng Q, Ottoboni L, Ying W, Waeber C, Sims JR, DeJager PL, Sagher O, Philbert MA, Xu X, Kesari S, Xie XS, Young GS. Multicolored Stain-free Histopathology with Coherent Raman Imaging. Laboratory Investigation 2012;92(11):1492-502.

80.     White NS, McDonald CR, Farid N, Kuperman J, Kesari S*, Dale AM. Improved conspicuity and delineation of high-grade primary and metastatic brain tumors using “restriction spectrum imaging”: Quantitative comparison with high b-value DWI and ADC. AJNR 2012 (epub).
*Co-Senior/corresponding author

81.     MacDonald CR, White NS, Farid N, Bartsch H, Lai G, Hagler DJ, Kesari S, Carter BS, Chen CC, Dale AM. Recovery of White Matter Tracts in Regions of Peritumoral Edema Using Restriction Spectrum Imaging. AJNR 2013; (in press).

82.     Yost SE, Pastorino S, Rozenzhak S, Smith EN, Chao YS, Jiang P, Kesari S*, Frazer K, Harismandy O. High-resolution mutational profiling suggests the genetic validity of glioblastoma patient-derived pre-clinical models. PLoS One 2013; (in press)
*Co-Senior/corresponding author

83.     Saria MG, Corle C, Hu J, Rudnick J, Phuphanich S, Mrugala MM, Crew LK, Bota DA, Dan Fu B, Kim RY, Brown T, Feely H, Brechlin J, Brown BD, Drappatz J, Wen PY, Chen CC, Carter B, Lee JW, Kesari S*. Retrospective analysis of the tolerability and activity of lacosamide in patients with brain tumors. J. Neurosurgery 2013 (in press).
*Senior/corresponding author

84.     Kothari P, MacDonald CR, White NS, Farid N, Bartsch H, Kesari S, Dale AM. Longitudinal Restriction Spectrum Imaging is Resistant to Pseudoresponse in Patients with High-Grade Gliomas treated with Bevacizumab AJNR 2013; (in press).

85.     Shi G, Cui W, Benchimol M, Liu Y, Mattrey R, Mukthavaram R, Kesari S, Esener S, Simberg D. Isolation of Rare Tumor Cells from Blood Cells with Buoyant Immuno-Microbubbles. PLoS ONE 2013; (in press)

86.     Zhu J, Larman HB, Gao G, Laserson U, Ciccia A, Pavlova N, Church G, Kesari S, Elledge SJ. PLATO: Parallel Analysis of in vitro Translated ORFs. Nature Biotechnology 2013 (in press)

87.     Nozawa A, Rivandi AH, Kesari S*, Hoh CK. Parametric metabolic FDG PET brain scans for the detection of brain tumors European Journal of Nuclear Medicine and Molecular Imaging 2013; (in press)*Co-Senior/corresponding author

ORIGINAL ARTICLES

PUBLISHED RESEARCH  BY SANTOSH KESARI